miRWoods: Enhanced precursor detection and stacked random forests for the sensitive detection of microRNAs
Fig 8
Novel microRNA families identified by miRWoods.
a hsa-novel-8 is a mirtron predicted for both MCF-7 sets where expression was decreased in the Dicer knockdown sets. b hsa-Novel-185 is a mirtron predicted within the human cell lines set and the MCF-7 (cytoplasmic fraction) set. It also shows reduced expression in the Dicer knockdown version of the MCF-7 set. c The structure of hsa-novel-8. d The structure of hsa-Novel-185. e Phylogeny comparing the LAMA5 intron and CHD3 intron for several mammals. f Novel miR predicted in bovine genome in an intron of TYK2. g novel predicted miR in the feline genome in the same intron of TYK2 h structure of novel feline miR. i structure of novel bovine miR. Eight nucleoties were removed from the 5' end, and two were added to the 3' end to match the feline hairpin precursor boundaries. j A phylogeny comparing the TYK2 intron in several mammals.