Fast uncertainty quantification for dynamic flux balance analysis using non-smooth polynomial chaos expansions
Fig 3
Accuracy of singularity time surrogate models.
RMSE versus the number of model evaluations (i.e., size of the experimental design) used to train the PCE model for (a) the glucose singularity tg and (b) the xylose singularity tz. The RMSE was estimated empirically from a validation set of 10,000 full DFBA simulations.