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A biophysical model of striatal microcircuits suggests gamma and beta oscillations interleaved at delta/theta frequencies mediate periodicity in motor control

Fig 5

Baseline SPN activity is characterized by β oscillations only in the D1 subnetwork under high DA conditions.

(A) Schematics depicting the baseline (i) and high DAergic tone (ii) conditions in an isolated SPN-only network. (B) Mean voltages for the D1 and D2 SPN populations in the two conditions. (C) Spectrograms of mean voltage for the D1 subpopulation (upper) and D2 subpopulation (lower). (D) Power spectral density of D1 and D2 population activity, averaged over 20 simulations. Shading represents standard deviation from the mean. Power spectra are derived using Thomson’s multitaper power spectral density (PSD) estimate (MATLAB function pmtm). (E) Raster plots of SPN population activity.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1007300.g005