DeepHiC: A generative adversarial network for enhancing Hi-C data resolution
Fig 2
DeepHiC enhances the interaction matrix, even in fine-grained textures, with low-sequence depth.
(a) Shown in the figures are real (first column), 1/16 downsampled (second column), Boost-HiC/HiCPlus/HiCNN-enhanced (third-fifth columns) and DeepHiC-enhanced (sixth column) interaction matrices in three different 1-Mb-width sub-regions from the GM12878 cell line at 10-kb resolution. (b) Enlarged heatmaps of smaller sub-regions (0.3Mb×0.3Mb, extracted from the matching coloured frames in (a) obtained from real high-resolution and DeepHiC-enhanced matrices.