Selective recruitment of cortical neurons by electrical stimulation
Fig 3
Estimation of the activation probability induced by surface stimulation.
An example of typical layer IV pyramidal cell is shown. For each cell, we assigned R, and Z (depth) parameters. Activating function identifies its trigger area (red markers), where the effective current is above threshold. Action potentials can be initiated in these segments and propagate along the axonal arborization. To populate a statistical set (to find the average probability of spiking), each cell reconstruction was shuffled by rotating and shifting along the vertical axis (indicated by bold arrows), and multiple reconstructions were considered for each cell type (up to a total of 561 cells, see S1 Table and Methods: Selecting cell reconstructions within available databases).