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A benchmark of computational CRISPR-Cas9 guide design methods

Fig 2

Reasons for rejection.

This plot shows, for each tool, the proportion of accepted guides that have been rejected by mm10db, and the reason for doing so. An asterisk (*) indicates the category relates to a rule implemented in mm10db for rejecting guides. mm10db is used as a reference point because it provides a reason for any guide it rejects.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1007274.g002