Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers
Fig 6
Visualization of model predictions.
Visualization of model predictions (a) neglecting pre-ATI ART regimen, using Eq (1), and (b) accounting for pre-ATI ART regimen, using Eq (2). The normalized times of last undetectable measurement and first detectable measurement are shown as line segments spanning the detection window per ATI study participant. Each detection window’s line segment is normalized by subtracting the associated model-predicted mean and dividing by the model-predicted standard deviation. Red and blue lines indicate detection windows that lie wholly outside one standard deviation, with color indicating whether the pre-ATI ART regimen is included (red) or excluded (blue) NNRTIs, while grey lines indicate detection windows that may be within one standard deviation of the mean.