Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling
Fig 3
The use of optimal parameters for HDDRs improves 3D modeling quality.
(A) and (B) GDT-HA and lDDT scores of the AS models built with σMOD (reported on the x-axis) and with optimal |Δdn| (y-axis) values. (C) and (D) GDT-HA and lDDT scores for the AM models obtained with MODELLER-generated (x-axis) and optimal (y-axis) HDDRs.