Assessing key decisions for transcriptomic data integration in biochemical networks
Fig 4
Preprocessing decisions influence the significance of tissue grouping at organ-system level.
We compared the mean Euclidean distance observed between tissues belonging to the same organ-system to the mean Euclidean distance for 10000 randomly selected groups with the same number of tissues. The significance of the grouping (P-value) is computed as the proportion of random distances lower than the observed distance for each organ-system.