Identifying important parameters in the inflammatory process with a mathematical model of immune cell influx and macrophage polarization
Fig 9
Results of perturbations in parameter kan.
Parameter kan, which models the rate of neutrophil apoptosis, was varied around its baseline value of kan = 7.108. The effects of variations on M1, M2, and neutrophils are shown. Values lower than baseline lead to a sustained inflammatory response from all immune cells while higher values shorten the time course of each.