Remarkable structural transformations of actin bundles are driven by their initial polarity, motor activity, crosslinking, and filament treadmilling
Fig 5
Schematic of preferred network morphologies under different values of triad.
Cartoon illustration of dominant network morphologies of bundles expected in a) unipolar and b) apolar initial configurations at different ranges of treadmilling factor namely χ = 0, 0>χ≤1.0 (0.1, 0.3, 0.6, 1.0) and χ>1.0 (3.0, 6.0, 10.0) Morphologies observed at discrete values of triad along with results from clustering (S5 Fig in S1 Text) were used to propose the map above. Colored voxels are used to represent distinct zones of preferred network morphologies expected. Dotted line represents uncertainty in the boundary. Dotted lines within white bands represent the crosslinker- and myosin-dependent boundaries between stable and unstable networks.