Remarkable structural transformations of actin bundles are driven by their initial polarity, motor activity, crosslinking, and filament treadmilling
Fig 1
The mechanical model of actin, α-actinin and myosin minifilaments in MEDYAN.
Double helix structure of actin filament is represented as a series of cylinders (red) connected together at hinges (black spheres). Stretching (Uistr), bending (Uibend) and cylinder-cylinder excluded volume (Uijvol) interactions are elaborated. Crosslinkers (green) and myosin MF (blue) experience stretching potentials (Uiα and UiMF respectively). More details are provided in the Methods section and the Supporting Methods (section 2 in S1 Text).