Modeling metabolic networks of individual bacterial agents in heterogeneous and dynamic soil habitats (IndiMeSH)
Fig 3
Distribution of obligate aerobic P. putida (cyan) and facultative anaerobic P. veronii (magenta) along the carbon-oxygen counter gradient from the central port to the peripheral ports.
Combined experimental results (boxplots, whiskers indicate minimum and maximum of data) and simulation results (shaded area with 95% of all cells, thick line represents mean) in a well connected, artificial pore network using IndiMeSH (left) and Monod parametrization (right). Segregation of facultative anaerobes into an anaerobically growing (central port, anoxic) and peripheral, aerobically growing subpopulation can be observed in the results using IndiMeSH which is absent in the results using Monod parametrization. The observed shift of obligate aerobes towards the periphery is due to the chosen canonical half saturation coefficient in IndiMeSH (0.05 mM) compared to the Monod half saturation coefficient in the original model (0.0063 mM).