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Modeling the daily rhythm of human pain processing in the dorsal horn

Fig 2

Response curve and NMDA activation plots [see Eq (3)].

A: Response functions of the projection (blue), excitatory (green), and inhibitory (red) neural populations for varying average input firing rates (on the x-axis). Parameters for these curves were chosen to match experiments presented in [21]. B: Activation curve for the NMDA-mediated synaptic input (M), shown as a fraction of the maximum synaptic weight gNMDA.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1007106.g002