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Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference

Fig 6

Cell biology evaluation of oncogenic properties of CSMD3 and ZHFX4.

A-B. The impact of knocking down CSMD3 and ZFHX4 on cell proliferation. C-D. The impact of knocking down CSMD3 and ZFHX4 on cell migration. E. Impact of ZFHX4 knockdown on apoptosis in PC3 cell line measured by Annexin V and propidium iodide (PI) staining.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1007088.g006