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A multi-scale model of gas transport in the lung to study heterogeneous lung ventilation during the multiple-breath washout test

Fig 3

Pressure-volume curve for trumpet lobule.

Lobular volume V_lb in function of the elastic pressure p_el as defined in Eq 3. The purple area indicates the reference pleural pressure range and the orange area indicates the nominal lobule volume range . In panel (a) the influence of the compliance modification parameter ϕ∈[0.5,1.5] is shown. For lobules with normal compliance (ϕ = 1, solid line) the elastic pressure curve intersects in the point . In panel (b) the effect of the non-linear parameter γ is shown. The parameter was chosen such that the elastic pressure curve intersects with the point (black dot). Note that ϕ = 1 was used for all graphs in panel (b).

doi: https://doi.org/10.1371/journal.pcbi.1007079.g003