Multiscale model of integrin adhesion assembly
Fig 4
Integrin activation rate enhances clustering and ligand binding.
(A) Average percentage of clustered integrins as a function of activation rate, ka, by varying ligand binding affinity, EIL, and keeping EII = 5 kBT. (B) Corresponding average percentage of ligand-bound integrins. Data are computed between 10–200 s of simulations from three independent runs. Error bars indicate standard deviation from the mean.