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Analyzing pharmacological intervention points: A method to calculate external stimuli to switch between steady states in regulatory networks

Fig 2

We see the active external stimuli u1 (activating P2Y12) and u2 (activating P2Y1) where the others are not active.

The others are u3 activating PTP, u4 inhibiting ThromR and u5 inhibiting Akt if active. The time is on the abscissa (t) and the activity level (A) is on the ordinate. The original Matlab output is without axis labeling.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1007075.g002