A new framework for assessing subject-specific whole brain circulation and perfusion using MRI-based measurements and a multi-scale continuous flow model
Fig 16
Relative sensitivity coefficients for the perfusion proportionality parameter α, porosities ϕa, ϕv, vascular permeabilities ka, kv, the pressure drop parameter γa, γv, and fluid viscosity μ investigated for the compartmental pressures pa, pv, the perfusion P, time to peak (TTP), and mean transit time (MTT) for the frog tongue.
Brighter values indicate higher sensitivity of the input parameter to the output parameter. Left: Relative sensitivity coefficient averaged over the voxels for the 3D human brain example. Right: Voxelwise, relative sensitivity coefficients from the frog tongue showing the relation between α and P.