A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data
Fig 5
Wide variability in individual codon translation rates in vivo.
(A) Probability density functions for translation times of AUU, GAC and UGG codons in Nissley dataset. Median translation times for AUU, GAC and UGG codon are 127, 208 and 331 ms, respectively. (B) The translation time profile of S. cerevisiae transcript YAL038W from Nissley dataset is shown between codon positions 150 and 450. AAG codon (colored red) is translated in 362.8 ms at the 196th codon position and in 58.6 ms at 413th codon position.