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Mathematical modelling reveals unexpected inheritance and variability patterns of cell cycle parameters in mammalian cells

Fig 3

Results of long term simulations.

(A) Dynamics of the time series of the Cdt1 and Geminin protein contents in a randomly chosen lineage of descendants of the ancestor cell. (B) Phase portrait of experimental and simulation data. Ten trajectories of cell cycle were randomly selected from the experiment (left) and simulation (right) data. In both cases, fluorescence levels were normalized to maximum values.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1007054.g003