Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions
Fig 6
Observed conformations of SDPE due to the flexibility of DHA in the fine-grained simulations.
A) An example configuration, where the DHA chain adapts to the A2AR surface. B) An example configuration, where the DHA chain penetrates into the core of A2AR. The DHA chain is shown in orange, the rest of the lipid (including the stearic acid chain) in yellow, and A2AR in green.