LASSI: A lattice model for simulating phase transitions of multivalent proteins
Fig 11
Phase behaviors of the branched multivalent systems for T* = 0.25.
(a) Full phase diagram, where the purple line denotes the proxy for the binodal and the green line is the proxy for the percolation line (see also the caption for Fig 7). The phase-separated region has an elliptical shape and we have a closed loop, which demonstrates re-entrant phase behavior, whereas the percolation line has a conical shape extending into much higher densities. The solid black lines denote contours of constant total concentration where L1 is the lowest concentration and L3 is the highest concentration. Note that both axes are represented in the log scale. (b, c) and ϕc curves as a function of relative stoichiometric ratio of N130 and rpL5 along the constant-concentration contours. (d) Plot of Λ vs. the apparent stoichiometry along lines L1, L2, and L3.