LASSI: A lattice model for simulating phase transitions of multivalent proteins
Fig 3
Distribution functions used for calculation of density inhomogeneity.
The data shown are obtained from 5 independent simulations for the An-Bn system with total protein concentration c = 6.89×10−5 voxels-1 and reduced temperature T* = 0.383. Error bars indicate standard deviations. (a) Pair distribution functions P(2)(r) and P0(2)(r), where the former is from the interacting system and the latter from the non-interacting system with chain connectivity (prior pair distribution function). Note that P(2)(r) shows two peaks, the first of which indicates dense phase formation. (b) Radial distribution function . This captures the droplet formation by a sharp and broad peak in the beginning. The inset shows rb where
intersects the line corresponding to
line, delineating between the dense and solution phases. The global density inhomogeneity measure,
, is obtained by integration of absolute deviation of
from 1.