LASSI: A lattice model for simulating phase transitions of multivalent proteins
Fig 2
Considerations that go into designing a coarse-grained model.
As discussed in the text, the choice of a coarse-grained model has at least three ingredients. These include the type of conformational space (lattice or off-lattice), the nature of the interactions among entities that are represented in the coarse-grained description (isotropic, anisotropic or fluctuating fields), and the parameterization approach. LASSI, as described here, is based on a lattice model that uses anisotropic interactions and a phenomenological model.