Neural crest streaming as an emergent property of tissue interactions during morphogenesis
Fig 3
Ectopic neural crest is able to invade normally NC-free territories and form streams.
(A-B) Illustration of autograft experiments showing the control (A) and ectopic-rotated (B) graft arrangements. (C-F) Control experiment after graft healing (C, t = 0) and t = 8h (D), 12h (E), and 16h (F) later. (G) Pseudo-colored overlay of control grafted embryos shown on (C-F). (H-K) Ectopic autograft after healing (H, t = 0) and t = 8h (I), 12h (J), and 16h (K) later. (L) Pseudo-colored overlay of ectopic grafts shown on (H-K). (M) Illustration of stream formation observed in control and ectopic graft experiments. ISH against Twist; arrowheads indicate streams in the grafted locations; ‘*’: eye / optic vesicle; braces indicate initial graft; scalebars: 300μm.