A system-wide network reconstruction of gene regulation and metabolism in Escherichia coli
Fig 4
Topological properties of the functional and vertex type-driven network partitions.
The functional partitions are denoted by the respective modules, metabolic domain (MD), regulatory domain (RD) and protein interface (PI). The vertex type-driven partitions are represented by the comprising vertex types, reaction (green hexagon), compound (blue square), gene (yellow circle), and protein (brown triangle). For each property, the module-specific coefficients and contributions (I, II, III) are presented, respectively. For the modularity, M, the overall network coefficient (Total) is shown as well as the best coefficient is underlined, the module-specific values correspond to the terms in the sum of Eq (1).