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Isolating and quantifying the role of developmental noise in generating phenotypic variation

Fig 7

Random phenotype variation.

The phenotype cloud for 1000 simulations showing the random variation of a single LALI-type, for either the A) linear or B) FitzHugh-Nagumo models. The representative LALI-type was chosen from the 50% neutral region of gecko pattern #682. (The location of this LALI-type is shown as a labeled white dot in Fig 8). The phenotypes of the 1000 simulations are indicated as gray disks in FA-EE phenotype space, while the 500 within the 50% radius of the phenotype cloud are outlined in purple. Three random phenotypes from the cloud are shown in red (see below). C, D) The pattern isolated from the image of Gecko #682 and the patterns of three simulated “clones” (patterns generated with the same LALI-type that is likely to yield pattern #682, but allowing random variation). The result is not necessarily ‘close’ to the pattern #682 (their locations in FA-EE space are indicated in red in the panels ‘A’ and ‘B’.) Horizontal bars indicate 0.5 cm.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1006943.g007