Isolating and quantifying the role of developmental noise in generating phenotypic variation
Fig 4
Overview of methods (Steps 0–2).
The L→P map is modeled by one of two computational reaction diffusion models. Due to developmental noise, one LALI-type probabilistically maps to many phenotypes (the ‘phenotype cloud’) and many LALI-types map to one phenotype (the ‘neutral region’ of the phenotype).