A benchmark-driven approach to reconstruct metabolic networks for studying cancer metabolism
Fig 4
Prediction of general cancer essential genes.
(A) Heatmap of enrichment p-values for predicted cell-line specific essential genes. The numbers indicate -log10 enrichment p-values. GEMs with insignificant p-values are shown in white. (B) Rank scores of the algorithms based on their significance and the number of GEMs with significant enrichment (as described in S2 Text).