Rich-club connectivity, diverse population coupling, and dynamical activity patterns emerging from local cortical circuits
Fig 8
Emergent, heterogeneous population coupling in the dynamical working regime of the local cortical circuit model.
(A) Spike-triggered population rate (stPR) for five representative neurons in a single trial. (B) stPR for the same five neurons but with spikes shuffled. Inset: distributions of stPR coefficients pooled from 10 trials before (black) and after (red) spike shuffling. The coefficients are defined as the stPR values at zero time lag normalized by the median value of the shuffled data. For each trial, 10 samples of 66 excitatory neurons are randomly chosen to match the sample size used in experimental studies [12]. Neurons are sampled from a circular area with a radius of 25 grid units (about 125 ¼m) for approximating the spike detection range of a single shank of silicon electrode array used in [12]. The results are not sensitive to the size of the sampling area or the number of sampled neurons. (C-D) stPRs for ζ = 1.15 and ζ = 0.7, respectively. Insets: shuffled stPRs. For ζ = 1.15, the model is shifted away from the working regime into the regular propagating wave state; while for ζ = 0.7, it is shifted into the irregular, asynchronous state.