Bayes-optimal estimation of overlap between populations of fixed size
Fig 3
Bayesian repertoire overlap consistently estimates true overlap.
Repertoires with true overlaps ranging from 0 to 60 were subsampled in simulations. As sampling rates increase from na = nb = 30 (left) to 40 (middle) and to 50 (right), the estimates of BRO (colored circles) approach the true values (dotted lines) symmetrically. Estimates from (crosses) approach the true values from below, systematically underestimating the true overlap. This bias is worse with lower sampling rates [7]. Similar results are found when na ≠ nb, and when the total repertoire sizes are different from each other (S1 Fig).