Evolution of interface binding strengths in simplified model of protein quaternary structure
Fig 5
Decision tree for heterotetramer.
The assembly graph has interaction strengths A and B. Each seed is a starting point for the decision tree, incrementally progressing until assembly terminates. In this situation, once a gray subunit is placed, assembly deterministically ends with the heterotetramer, rendering further branching unnecessary. The lower branchings have an extra weighting factor of two, due to two indistinguishable assembly steps.