Robustness of respiratory rhythm generation across dynamic regimes
Fig 13
Period is insensitive to drive to the PiCo and to the presence of PiCo.
Period T (black), expiratory duration TE (red), and inspiratory duration TI (blue) versus (A,B) PiCo drive parameter (c15) or (C,D) drive to the post-I unit (c13), relative to its baseline value of 0.58 (denoted by 0 here). In (A,B), dashed-dotted vertical black lines separate intervals of c15 values corresponding to different types of PiCo intrinsic dynamics. In (A,C), pre-I is intrinsically oscillatory (c11 = −0.03); in (B,D), pre-I is intrinsically tonic (c11 = 0.01). Axis ranges in (C,D) are identical to those in Fig 9 (middle row) except for extension to more negative relative values of c13 here, since rhythmicity persists down to these lower levels.