Robustness of respiratory rhythm generation across dynamic regimes
Fig 8
Input to the preBötC pre-I node controls period by modulating TE.
(A): Period (black), inspiratory duration (blue), and expiratory duration (red) versus drive to pre-I, c11, over the range of c11 for which network rhythms were maintained. Values of c11 where the pre-I unit is intrinsically oscillatory or tonic are separated (dash-dotted black line) and labeled. (B-C): Same curves versus the value of inhibition from post-I to pre-I, b31, relative to its baseline value (0.125; here labeled as 0) over the range where network rhythmicity is maintained; results are shown when the pre-I is intrinsically oscillatory (B), with c11 = −0.03, and tonic (C), with c11 = 0.01. Increasing b31 prolongs the time until pre-I activity can rise, leading to longer expiratory phase durations and periods.