Robustness of respiratory rhythm generation across dynamic regimes
Fig 5
Parameter-dependence of model output.
In all cases, gNaP refers to the persistent sodium conductance for the pre-I unit (i.e., gNaP,exc from the Methods section). (A) Grey scale in boxes codes period of full rhythm, with longest period given by palest shades (color bar, periods in seconds). For parameter values in the unboxed white region, the network is not rhythmic. For parameter values below the red curve, the pre-I neuron is intrinsically oscillatory. (B) Grey scale codes amplitudes, with largest amplitude given by darkest shades (color bar, amplitudes measured as maximum minus minimum of pre-I output, f(V1)). Red curve as in upper left. (C) Grey-coded inspiratory phase duration (seconds), measured as time between increased and subsequent decreases of V1 through a threshold of -35 mV. (D) Grey-coded expiratory phase duration (seconds), measured as the period minus the inspiratory phase duration. The blue boxed regions are explained in the text.