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A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Fig 5

The workflow integrates multistep 0D (single-cell), 1D and 2D model simulations in a single automated process.

A. Simulated results of single-cell action potential (bottom panel). B. The pseudo ECG (bottom panel), and C. Six distinct time snapshots of 2D action potential wave propagation (bottom panel) from endocardial region (left) to epicardial region (right), with a linear decrease in APDs.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1006856.g005