Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity
Fig 3
The particle-based model produces different calcium activity regimes depending on parameter values.
Color-coded map of variation of the peak frequency, expressed as the number of calcium peaks per MC time step (A) and as the maximal number of IP3R channel open per peak (B). The color scale is given for each map. The black area corresponds to the stationary regime. Note that the x and y-axis scales in (A) and (B) are not regularly spaced. The symbols ★, ◼ and ● locate parameter pairs that are illustrative of the three dynamical regimes shown in (C): stationary (★, μ = 5, a1 = 0.5), blips (◼, μ = 25, a1 = 2) and puffs (●, μ = 75, a1 = 7). Red crosses show the locations of peaks from automatic detection. DCa = DIP3 = ∞, η = 1, Rγ = 200.