3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients
Fig 5
Representation of the proteins that have multiple interfaces used by different subsets of partners and one interface shared by multiple partners.
(A) The left part represents an example for proteins having multiple interfaces (PTPN11) with different subset of partners and the right part represents an example for proteins having one interface (TP53) shared by different partners. (B) The organization of RB1 and PIK3CA interface mutations are represented as a network where the nodes are mutations and proteins and the edges between mutations represents at least one shared partners between two mutations. The edges between proteins and mutations represents the interface (C) The table for numbers of mutations in each interface type.