Augmenting subnetwork inference with information extracted from the scientific literature
Fig 5
Overview of the NR2F1 subnetwork inference task.
The first panel displays a background network composed of the source NR2F1 (black), target DE genes (blue), and interactions (dashed and solid lines). Transcription factors are identified as bright magenta nodes. The background network is augmented by a set of Literome interactions (purple arrows). The second panel displays the inferred subnetwork. Orange nodes show elements that are not considered source, transcription factors, or target nodes; we refer to these as intermediate nodes in the inferred subnetwork.