Modelling the transport of fluid through heterogeneous, whole tumours in silico
Fig 6
Data-fitted curves of IFP (top) and IFV (bottom) for modulation of interstitial model parameters: (a, e) p∞ (mmHg), (b, f) σ, (c, g) Lp(cm / mmHg s) and (d, h) κ (cm2 / mmHg s).
Arrows indicate increasing parameter values, with exception of (d) in which a range of κ (cm2 / mmHg s) is indicated. IFP profile gradients across LS2 sensitivity analysis of (a) far-field pressure, p∞, (b) oncotic reflection coefficient, σ, (c) vascular hydraulic conductivity, Lp, and (d) interstitial hydraulic conductivity, κ (cm2 / mmHg s). Arrows indicate increasing values of the given parameter and colours in each column indicate the equivalent simulation.