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16S rRNA sequence embeddings: Meaningful numeric feature representations of nucleotide sequences that are convenient for downstream analyses

Fig 9

Distribution of pairwise cosine similarity for k-mer, sequence, and sample embeddings of the American Gut data.

Sequence and sample embeddings were calculated from 21 randomly selected (7 for each body site) samples. k-mer embeddings were those used during training with the GreenGenes sequences. Shown are distributions of pairwise cosine similarities as a function of k-mer size (rows), denoising (blue versus red), and embedding space (columns).

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1006721.g009