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A stochastic simulation of skeletal muscle calcium transients in a structurally realistic sarcomere model using MCell

Fig 7

Fenestrated SR, SERCA activation at peak [Ca2+].

SERCA pumps bound with 2 Ca2+ ions are white, SERCA bound with a single Ca2+ are orange, unbound SERCA are dark orange, RYR release sites are cyan (single myosin and actin rendered for scale).

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1006712.g007