New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx
Fig 4
DE genes in uterine cancer compared to healthy uterine tissue samples.
A) The workflow illustrates the steps and TCGAbiolinks functions to be used for this case study. B-C) In the volcano plot, the up-regulated genes with logFC higher than 5 (B) or the down-regulated genes with logFC lower than -5 (C) are shown as a result of DEA carried out using the limma pipeline comparing primary tumor samples from TCGA-UCS and normal uterine tissue samples from GTEx.