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Exploring chromatin hierarchical organization via Markov State Modelling

Fig 8

High-affinity clusters enriched in various histone modifications.

Node sizes represent the factor Z scores, and edge widths represent affinity values. The following histone modifications are considered; (A) H3K9ac, (B) H3K9me3, (C) H3K27ac, (D) H3K27me3, (E) H3K4me1, and (F) H3K4me3. In each case, only partitions with factor Z-scores above 2 and only edges connecting partition pairs with high affinity C > 2 are shown.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1006686.g008