A computational model for gonadotropin releasing cells in the teleost fish medaka
Fig 9
Fitted kinetics for the Ca2+ current.
(A) ICa evoked by the activation protocol. (B) ICa evoked by the deactivation protocol. (A-B) Voltage protocols are shown below the recorded currents, and all panels show a series of experiments (traces). The current-traces were low-pass filtered with a cutoff-frequency of 300 Hz. (C) Voltage dependence of steady-state activation, normalized so that the activation curve had a maximum value of 1 (assuming fully open channels). (D) Activation time constant. Red data points were estimated from the deactivation protocol (B), while blue data points were estimated using the activation protocol (A). Dashed lines in (C-D) denote the kinetics scheme when corrected for a liquid junction potential of −15 mV for the experimental conditions used for recording Ca2+ currents.