A computational model for gonadotropin releasing cells in the teleost fish medaka
Fig 3
The spontaneous activity of the medaka gonadotroph model for different levels of BK-expression. (A1) Spontaneous activity under control conditions, where gBK was maximally expressed (blue curve, gBK = 0.31mS/cm2). AP firing was completely abolished by setting gNa = 0, mimicking the effect of TTX (red curve). (B1-F1) Simulations with gBK reduced to fractions (indicated above panels) of the maximum value. Reductions in gBK consistently lead to broader APs. (A2-F2) Close-ups of the first APs in seen in A1-F1.