< Back to Article

A mathematical model of calcium dynamics: Obesity and mitochondria-associated ER membranes

Fig 10

Effects of increased IPR activity on Ca²⁺ oscillations.

Oscillations of (A) cytosolic and (B) mitochondrial Ca²⁺ concentrations generated from the control model, in blue, and the model with the increased k_IPR and k_nIPR, in red dashed. The model was given continuous stimulation of IP₃ with P_s = 0.3 μM.

doi: https://doi.org/10.1371/journal.pcbi.1006661.g010