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Molecular basis for the increased affinity of an RNA recognition motif with re-engineered specificity: A molecular dynamics and enhanced sampling simulations study

Table 5

Hydrogen bonds at the binding interface of the Rbfox*•pre-miR20b* complex during simulations.

The average donor-acceptor distances and angles are calculated over the entire simulation ensemble for the trajectory frames in which the individual H-bonds are observed and the interactions are further characterized by their occupancy in the individual simulation trajectories. The trajectories are numbered as in Table 1.

Table 5

doi: https://doi.org/10.1371/journal.pcbi.1006642.t005