Molecular basis for the increased affinity of an RNA recognition motif with re-engineered specificity: A molecular dynamics and enhanced sampling simulations study
Fig 2
Fluctuations of the PAD angle in the simulations of free (top; see Table 1, sim. 1) and bound Rbfox protein (bottom; see Table 1, sim.
9–13). F indicates fluctuations; t short transitions and T long transitions. The structured regions of the protein are highlighted: the grey and yellow regions correspond to the β-strands and helices, respectively.